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WACS: improving ChIP-seq peak calling by optimally weighting controls
BACKGROUND: Chromatin immunoprecipitation followed by high throughput sequencing (ChIP-seq), initially introduced more than a decade ago, is widely used by the scientific community to detect protein/DNA binding and histone modifications across the genome. Every experiment is prone to noise and bias,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885521/ https://www.ncbi.nlm.nih.gov/pubmed/33588754 http://dx.doi.org/10.1186/s12859-020-03927-2 |