Low expression of NSD1, NSD2, and NSD3 define a subset of human papillomavirus-positive oral squamous carcinomas with unfavorable prognosis

BACKGROUND: Frequent mutations in the nuclear receptor binding SET domain protein 1 (NSD1) gene have been observed in head and neck squamous cell carcinomas (HNSCC). NSD1 encodes a histone 3 lysine-36 methyltransferase. NSD1 mutations are correlated with improved clinical outcomes and increased sens...

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Detalles Bibliográficos
Autores principales: Gameiro, Steven F., Ghasemi, Farhad, Zeng, Peter Y. F., Mundi, Neil, Howlett, Christopher J., Plantinga, Paul, Barrett, John W., Nichols, Anthony C., Mymryk, Joe S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885607/
https://www.ncbi.nlm.nih.gov/pubmed/33588906
http://dx.doi.org/10.1186/s13027-021-00347-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885607/
https://www.ncbi.nlm.nih.gov/pubmed/33588906
http://dx.doi.org/10.1186/s13027-021-00347-6

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