Hyaluronic Acid Conjugated Metformin-Phospholipid Sonocomplex: A Biphasic Complexation Approach to Correct Hypoxic Tumour Microenvironment

PURPOSE: Development of hyaluronic acid conjugated metformin-phospholipid sonocomplexes (HA-MPS), a biphasic complexation product compiled for enhancing both the lipophilicity and targeting potential of Metformin (MET) to CD44 receptors on pancreatic cancer. METHODS: MET was chemically conjugated to...

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Detalles Bibliográficos
Autores principales: Farag, Michael M, Abd El Malak, Nevine S, Yehia, Soad A, Ahmed, Mohammed A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885809/
https://www.ncbi.nlm.nih.gov/pubmed/33603365
http://dx.doi.org/10.2147/IJN.S297634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885809/
https://www.ncbi.nlm.nih.gov/pubmed/33603365
http://dx.doi.org/10.2147/IJN.S297634

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