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Direct activation of endothelial cells by SARS-CoV-2 nucleocapsid protein is blocked by Simvastatin

Emerging evidence suggests that endothelial activation plays a central role in the pathogenesis of acute respiratory distress syndrome (ARDS) and multi-organ failure in patients with COVID-19. However, the molecular mechanisms underlying endothelial activation in COVID-19 patients remain unclear. In...

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Detalles Bibliográficos
Autores principales: Qian, Yisong, Lei, Tianhua, Patel, Parth S., Lee, Chi H, Monaghan-Nichols, Paula, Xin, Hong-Bo, Qiu, Jianming, Fu, Mingui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885915/
https://www.ncbi.nlm.nih.gov/pubmed/33594363
http://dx.doi.org/10.1101/2021.02.14.431174