Genome-wide landscape of RNA-binding protein target site dysregulation reveals a major impact on psychiatric disorder risk

Despite the strong genetic basis of psychiatric disorders, the underlying molecular mechanisms remain largely unmapped. RNA-binding proteins (RBPs) are responsible for most post-transcriptional regulation, from splicing to translational to localization. RBPs thus act as key gatekeepers of cellular h...

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Detalles Bibliográficos
Autores principales: Park, Christopher Y., Zhou, Jian, Wong, Aaron K., Chen, Kathleen M., Theesfeld, Chandra L., Darnell, Robert B., Troyanskaya, Olga G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886016/
https://www.ncbi.nlm.nih.gov/pubmed/33462483
http://dx.doi.org/10.1038/s41588-020-00761-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886016/
https://www.ncbi.nlm.nih.gov/pubmed/33462483
http://dx.doi.org/10.1038/s41588-020-00761-3

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