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Recent advances in PTEN signalling axes in cancer

In over two decades since the discovery of phosphatase and tensin homologue deleted on chromosome 10 (PTEN), nearly 18,000 publications have attempted to elucidate its functions and roles in normal physiology and disease. The frequent disruption of PTEN in cancer cells was a strong indication that i...

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Detalles Bibliográficos
Autores principales: Chow, Jonathan Tak-Sum, Salmena, Leonardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculty Opinions Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886076/
https://www.ncbi.nlm.nih.gov/pubmed/33659963
http://dx.doi.org/10.12703/r/9-31