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Self-Nanoemulsifying Drug Delivery System of Genkwanin: A Novel Approach for Anti-Colitis-Associated Colorectal Cancer

PURPOSE: The aim of the present study was to develop an optimized Genkwanin (GKA)-loaded self-nanoemulsifying drug delivery system (SNEDDS) formulation to enhance the solubility, intestinal permeability, oral bioavailability and anti-colitis-associated colorectal cancer (CAC) activity of GKA. METHOD...

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Detalles Bibliográficos
Autores principales: Yin, Hua-Feng, Yin, Chun-Ming, Ouyang, Ting, Sun, Shu-Ding, Chen, Wei-Guo, Yang, Xiao-Lin, He, Xin, Zhang, Chun-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886095/
https://www.ncbi.nlm.nih.gov/pubmed/33603345
http://dx.doi.org/10.2147/DDDT.S292417