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Non-permissive human conventional CD1c(+) dendritic cells enable trans-infection of human primary renal tubular epithelial cells and protect BK polyomavirus from neutralization

The BK polyomavirus (BKPyV) is a ubiquitous human virus that persists in the renourinary epithelium. Immunosuppression can lead to BKPyV reactivation in the first year post-transplantation in kidney transplant recipients (KTRs) and hematopoietic stem cell transplant recipients. In KTRs, persistent D...

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Detalles Bibliográficos
Autores principales: Sikorski, Mathieu, Coulon, Flora, Peltier, Cécile, Braudeau, Cécile, Garcia, Alexandra, Giraud, Matthieu, Renaudin, Karine, Kandel-Aznar, Christine, Nedellec, Steven, Hulin, Philippe, Branchereau, Julien, Véziers, Joëlle, Gaboriaud, Pauline, Touzé, Antoine, Burlaud-Gaillard, Julien, Josien, Régis, McIlroy, Dorian, Bressollette-Bodin, Céline, Halary, Franck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886149/
https://www.ncbi.nlm.nih.gov/pubmed/33592065
http://dx.doi.org/10.1371/journal.ppat.1009042