Angiotensin-converting enzyme 2 (ACE2) expression increases with age in patients requiring mechanical ventilation

Mortality due to Covid-19 is highly associated with advanced age, owing in large part to severe lower respiratory tract infection. SARS-CoV-2 utilizes the host ACE2 receptor for infection. Whether ACE2 abundance in the lung contributes to age-associated vulnerability is currently unknown. We set out...

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Detalles Bibliográficos
Autores principales: Baker, Steven Andrew, Kwok, Shirley, Berry, Gerald J., Montine, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886150/
https://www.ncbi.nlm.nih.gov/pubmed/33592054
http://dx.doi.org/10.1371/journal.pone.0247060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886150/
https://www.ncbi.nlm.nih.gov/pubmed/33592054
http://dx.doi.org/10.1371/journal.pone.0247060

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