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Angiotensin-converting enzyme 2 (ACE2) expression increases with age in patients requiring mechanical ventilation
Mortality due to Covid-19 is highly associated with advanced age, owing in large part to severe lower respiratory tract infection. SARS-CoV-2 utilizes the host ACE2 receptor for infection. Whether ACE2 abundance in the lung contributes to age-associated vulnerability is currently unknown. We set out...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886150/ https://www.ncbi.nlm.nih.gov/pubmed/33592054 http://dx.doi.org/10.1371/journal.pone.0247060 |