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The anti-arthritis effect of sulforaphane, an activator of Nrf2, is associated with inhibition of both B cell differentiation and the production of inflammatory cytokines

Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is an important transcription factor that plays a pivotal role in cellular defense against oxidative injury. Nrf2 signaling is involved in attenuating autoimmune disorders such as rheumatoid arthritis (RA). B cells play several roles in the pathogen...

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Detalles Bibliográficos
Autores principales: Moon, Su-Jin, Jhun, Jooyeon, Ryu, Jaeyoon, Kwon, Ji ye, Kim, Se-Young, Jung, KyoungAh, Cho, Mi-La, Min, Jun-Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886167/
https://www.ncbi.nlm.nih.gov/pubmed/33592002
http://dx.doi.org/10.1371/journal.pone.0245986