Gene expression profiling identifies FLT3 mutation-like cases in wild-type FLT3 acute myeloid leukemia

BACKGROUND: FLT3 mutation is present in 25–30% of all acute myeloid leukemias (AML), and it is associated with adverse outcome. FLT3 inhibitors have shown improved survival results in AML both as upfront treatment and in relapsed/refractory disease. Curiously, a variable proportion of wild-type FLT3...

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Detalles Bibliográficos
Autores principales: Mosquera Orgueira, Adrián, Peleteiro Raíndo, Andrés, Cid López, Miguel, Antelo Rodríguez, Beatriz, Díaz Arias, José Ángel, Ferreiro Ferro, Roi, Alonso Vence, Natalia, Bendaña López, Ángeles, Abuín Blanco, Aitor, Bao Pérez, Laura, Melero Valentín, Paula, González Pérez, Marta Sonia, Cerchione, Claudio, Martinelli, Giovanni, Montesinos Fernández, Pau, Pérez Encinas, Manuel Mateo, Bello López, José Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886212/
https://www.ncbi.nlm.nih.gov/pubmed/33592069
http://dx.doi.org/10.1371/journal.pone.0247093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886212/
https://www.ncbi.nlm.nih.gov/pubmed/33592069
http://dx.doi.org/10.1371/journal.pone.0247093

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