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Gene expression profiling identifies FLT3 mutation-like cases in wild-type FLT3 acute myeloid leukemia
BACKGROUND: FLT3 mutation is present in 25–30% of all acute myeloid leukemias (AML), and it is associated with adverse outcome. FLT3 inhibitors have shown improved survival results in AML both as upfront treatment and in relapsed/refractory disease. Curiously, a variable proportion of wild-type FLT3...
Autores principales: | Mosquera Orgueira, Adrián, Peleteiro Raíndo, Andrés, Cid López, Miguel, Antelo Rodríguez, Beatriz, Díaz Arias, José Ángel, Ferreiro Ferro, Roi, Alonso Vence, Natalia, Bendaña López, Ángeles, Abuín Blanco, Aitor, Bao Pérez, Laura, Melero Valentín, Paula, González Pérez, Marta Sonia, Cerchione, Claudio, Martinelli, Giovanni, Montesinos Fernández, Pau, Pérez Encinas, Manuel Mateo, Bello López, José Luis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886212/ https://www.ncbi.nlm.nih.gov/pubmed/33592069 http://dx.doi.org/10.1371/journal.pone.0247093 |
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