Cargando…

Corticosteroid-binding-globulin (CBG)-deficient mice show high pY216-GSK3β and phosphorylated-Tau levels in the hippocampus

Corticosteroid-binding globulin (CBG) is the specific carrier of circulating glucocorticoids, but evidence suggests that it also plays an active role in modulating tissue glucocorticoid activity. CBG polymorphisms affecting its expression or affinity for glucocorticoids are associated with chronic p...

Descripción completa

Detalles Bibliográficos
Autores principales: Gulfo, José, Pérez de San Román, Joana, Ledda, Angelo, Junyent, Felix, Ramírez, María J., Gil-Bea, Francisco J., Esteve, Montserrat, Grasa, Mar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886218/
https://www.ncbi.nlm.nih.gov/pubmed/33592009
http://dx.doi.org/10.1371/journal.pone.0246930