A pipeline to evaluate inhibitors of the Pseudomonas aeruginosa exotoxin U

Pseudomonas aeruginosa has recently been highlighted by the World Health Organisation (WHO) as a major threat with high priority for the development of new therapies. In severe P. aeruginosa infections, the phospholipase activity of the type 3 secretion system toxin, ExoU, induces lysis of target ho...

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Detalles Bibliográficos
Autores principales: Foulkes, Daniel M., McLean, Keri, Zheng, Yalin, Sarsby, Joscelyn, Haneef, Atikah S., Fernig, David G., Winstanley, Craig, Berry, Neil, Kaye, Stephen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Enzymology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886320/
https://www.ncbi.nlm.nih.gov/pubmed/33459338
http://dx.doi.org/10.1042/BCJ20200780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886320/
https://www.ncbi.nlm.nih.gov/pubmed/33459338
http://dx.doi.org/10.1042/BCJ20200780

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