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Imbalanced turnover of collagen type III is associated with disease progression and mortality in high-risk chronic kidney disease patients
BACKGROUND: Tubulointerstitial fibrosis is a major pathological feature in chronic kidney disease (CKD) and collagen type III (COL3) is a major component of the renal fibrotic scar. We hypothesized that a dysregulated turnover of COL3 is an important determinant of CKD progression. We assessed the r...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886548/ https://www.ncbi.nlm.nih.gov/pubmed/33623684 http://dx.doi.org/10.1093/ckj/sfz174 |