Characterization and Validation of Arg286 Residue of IL-1RAcP as a Potential Drug Target for Osteoarthritis

Osteoarthritis (OA) is the most common form of arthritis and the fastest growing cause of chronic disability in the world. Formation of the ternary IL-1β /IL-1R1/IL-1RAcP protein complex and its downstream signaling has been implicated in osteoarthritis pathology. Current OA therapeutic approaches t...

Descripción completa

Detalles Bibliográficos
Autores principales: Dailing, Angela, Mitchell, Kelsey, Vuong, Ngoc, Lee, Kyung Hyeon, Joshi, Reva, Espina, Virginia, Haymond Still, Amanda, Gottschalk, Carter J., Brown, Anne M., Paige, Mikell, Liotta, Lance A., Luchini, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886681/
https://www.ncbi.nlm.nih.gov/pubmed/33614593
http://dx.doi.org/10.3389/fchem.2020.601477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886681/
https://www.ncbi.nlm.nih.gov/pubmed/33614593
http://dx.doi.org/10.3389/fchem.2020.601477

Ejemplares similares