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Plasmodium falciparum cGMP-Dependent Protein Kinase – A Novel Chemotherapeutic Target
The primary effector of cGMP signaling in Plasmodium is the cGMP-dependent protein kinase (PKG). Work in human-infective Plasmodium falciparum and rodent-infective Plasmodium berghei has provided biological validation of P. falciparum PKG (PfPKG) as a drug target for treating and/or protecting again...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886688/ https://www.ncbi.nlm.nih.gov/pubmed/33613463 http://dx.doi.org/10.3389/fmicb.2020.610408 |