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Plasmodium falciparum cGMP-Dependent Protein Kinase – A Novel Chemotherapeutic Target

The primary effector of cGMP signaling in Plasmodium is the cGMP-dependent protein kinase (PKG). Work in human-infective Plasmodium falciparum and rodent-infective Plasmodium berghei has provided biological validation of P. falciparum PKG (PfPKG) as a drug target for treating and/or protecting again...

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Detalles Bibliográficos
Autores principales:	Rotella, David, Siekierka, John, Bhanot, Purnima
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886688/ https://www.ncbi.nlm.nih.gov/pubmed/33613463 http://dx.doi.org/10.3389/fmicb.2020.610408

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