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Molecular and functional profiling of apical versus basolateral small extracellular vesicles derived from primary human proximal tubular epithelial cells under inflammatory conditions

Proximal tubular epithelial cells (PTEC) are central players in inflammatory kidney diseases. However, the complex signalling mechanism/s via which polarized PTEC mediate disease progression are poorly understood. Small extracellular vesicles (sEV), including exosomes, are recognized as fundamental...

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Detalles Bibliográficos
Autores principales: Wang, Xiangju, Wilkinson, Ray, Kildey, Katrina, Ungerer, Jacobus P. J., Hill, Michelle M., Shah, Alok K., Mohamed, Ahmed, Dutt, Mriga, Molendijk, Jeffrey, Healy, Helen, Kassianos, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886702/
https://www.ncbi.nlm.nih.gov/pubmed/33643548
http://dx.doi.org/10.1002/jev2.12064