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Participation of the HIM1 gene of yeast Saccharomyces cerevisiae in the error-free branch of post-replicative repair and role Polη in him1-dependent mutagenesis

In eukaryotes, DNA damage tolerance (DDT) is determined by two repair pathways, homologous repair recombination (HRR) and a pathway controlled by the RAD6-epistatic group of genes. Monoubiquitylation of PCNA mediates an error-prone pathway, whereas polyubiquitylation stimulates an error-free pathway...

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Detalles Bibliográficos
Autores principales: Alekseeva, E. A., Evstyukhina, T. A., Peshekhonov, V. T., Korolev, V. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886746/
https://www.ncbi.nlm.nih.gov/pubmed/33128582
http://dx.doi.org/10.1007/s00294-020-01115-6