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How does hepatic lipid accumulation lead to lipotoxicity in non-alcoholic fatty liver disease?

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD), characterized as excess lipid accumulation in the liver which is not due to alcohol use, has emerged as one of the major health problems around the world. The dysregulated lipid metabolism creates a lipotoxic environment which promotes the devel...

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Detalles Bibliográficos
Autores principales: Geng, Yana, Faber, Klaas Nico, de Meijer, Vincent E., Blokzijl, Hans, Moshage, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer India 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886759/
https://www.ncbi.nlm.nih.gov/pubmed/33548031
http://dx.doi.org/10.1007/s12072-020-10121-2