Preparation, Characterization, Pharmacokinetic, and Therapeutic Potential of Novel 6-Mercaptopurine-Loaded Oral Nanomedicines for Acute Lymphoblastic Leukemia

BACKGROUND: Acute lymphoblastic leukemia (ALL) is the most common hematologic malignancy in children. It requires a long and rigorous course of chemotherapy treatments. 6-Mercaptopurine (6-MP) is one of the primary drugs used in chemotherapy. Unfortunately, its efficacy has been limited due to its i...

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Detalles Bibliográficos
Autores principales: Zou, Yaru, Mei, Dong, Yuan, Jinjie, Han, Jiaqi, Xu, Jiamin, Sun, Ning, He, Huan, Yang, Changqing, Zhao, Libo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886780/
https://www.ncbi.nlm.nih.gov/pubmed/33603372
http://dx.doi.org/10.2147/IJN.S290466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886780/
https://www.ncbi.nlm.nih.gov/pubmed/33603372
http://dx.doi.org/10.2147/IJN.S290466

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