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A two-herb formula inhibits hyperproliferation of rheumatoid arthritis fibroblast-like synoviocytes

Fibroblast-like synoviocytes (FLS) play a pathogenic role in rheumatoid arthritis (RA). STAT3 signaling is activated in FLS of RA patients (RA-FLS), which in turn causes RA-FLS hyperproliferation. RL is a traditional remedy for treating inflammatory diseases in China. It comprises Rosae Multiflorae...

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Detalles Bibliográficos
Autores principales: Chen, Ying-Jie, Liu, Yu-Xi, Wu, Jia-Ying, Li, Chun-Yu, Tang, Min-Min, Bai, Lu, Fu, Xiu-Qiong, Li, Jun-Kui, Chou, Ji-Yao, Yin, Cheng-Le, Wang, Ya-Ping, Bai, Jing-Xuan, Wu, Ying, Wang, Xiao-Qi, Yu, Zhi-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886911/
https://www.ncbi.nlm.nih.gov/pubmed/33594167
http://dx.doi.org/10.1038/s41598-021-83435-2