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Raman spectroscopy and group and basis-restricted non negative matrix factorisation identifies radiation induced metabolic changes in human cancer cells

This work combines single cell Raman spectroscopy (RS) with group and basis restricted non-negative matrix factorisation (GBR-NMF) to identify individual biochemical changes associated with radiation exposure in three human cancer cell lines. The cell lines analysed were derived from lung (H460), br...

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Detalles Bibliográficos
Autores principales: Milligan, Kirsty, Deng, Xinchen, Shreeves, Phillip, Ali-Adeeb, Ramie, Matthews, Quinn, Brolo, Alexandre, Lum, Julian J., Andrews, Jeffrey L., Jirasek, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886912/
https://www.ncbi.nlm.nih.gov/pubmed/33594122
http://dx.doi.org/10.1038/s41598-021-83343-5