Improved Functionality of Exhausted Intrahepatic CXCR5+ CD8+ T Cells Contributes to Chronic Antigen Clearance Upon Immunomodulation

Chronic hepatotropic viral infections are characterized by exhausted CD8+ T cells in the presence of cognate antigen in the liver. The impairment of T cell response limits the control of chronic hepatotropic viruses. Immune-modulatory strategies are attractive options to re-invigorate exhausted T ce...

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Detalles Bibliográficos
Autores principales: Kumashie, Kingsley Gideon, Cebula, Marcin, Hagedorn, Claudia, Kreppel, Florian, Pils, Marina C., Koch-Nolte, Friedrich, Rissiek, Björn, Wirth, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886981/
https://www.ncbi.nlm.nih.gov/pubmed/33613516
http://dx.doi.org/10.3389/fimmu.2020.592328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886981/
https://www.ncbi.nlm.nih.gov/pubmed/33613516
http://dx.doi.org/10.3389/fimmu.2020.592328

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