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Nontrivial Replication of Loci Detected by Multi-Trait Methods

The ever-growing genome-wide association studies (GWAS) have revealed widespread pleiotropy. To exploit this, various methods that jointly consider associations of a genetic variant with multiple traits have been developed. Most efforts have been made concerning improving GWAS discovery power. Howev...

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Detalles Bibliográficos
Autores principales: Ning, Zheng, Tsepilov, Yakov A., Sharapov, Sodbo Zh., Wang, Zhipeng, Grishenko, Alexander K., Feng, Xiao, Shirali, Masoud, Joshi, Peter K., Wilson, James F., Pawitan, Yudi, Haley, Chris S., Aulchenko, Yurii S., Shen, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886991/
https://www.ncbi.nlm.nih.gov/pubmed/33613642
http://dx.doi.org/10.3389/fgene.2021.627989