Phosphorylation of the proline-rich domain of WAVE3 drives its oncogenic activity in breast cancer

Post-translational modification of proteins, such as tyrosine phosphorylation, plays a major role in driving the oncogenic activity of oncogenes. WAVE3 (WASF3), an adaptor and actin cytoskeleton remodeling protein, contributes to cell migration, cancer cell invasion, and metastasis. WAVE3 plays a vi...

Descripción completa

Detalles Bibliográficos
Autores principales: Kansakar, Urna, Wang, Wei, Markovic, Vesna, Sossey-Alaoui, Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887190/
https://www.ncbi.nlm.nih.gov/pubmed/33594155
http://dx.doi.org/10.1038/s41598-021-83479-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887190/
https://www.ncbi.nlm.nih.gov/pubmed/33594155
http://dx.doi.org/10.1038/s41598-021-83479-4

Ejemplares similares