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Phosphorylation of the proline-rich domain of WAVE3 drives its oncogenic activity in breast cancer

Post-translational modification of proteins, such as tyrosine phosphorylation, plays a major role in driving the oncogenic activity of oncogenes. WAVE3 (WASF3), an adaptor and actin cytoskeleton remodeling protein, contributes to cell migration, cancer cell invasion, and metastasis. WAVE3 plays a vi...

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Detalles Bibliográficos
Autores principales:	Kansakar, Urna, Wang, Wei, Markovic, Vesna, Sossey-Alaoui, Khalid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887190/ https://www.ncbi.nlm.nih.gov/pubmed/33594155 http://dx.doi.org/10.1038/s41598-021-83479-4

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