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Macrophage-derived EDA-A2 inhibits intestinal stem cells by targeting miR-494/EDA2R/β-catenin signaling in mice

The mucosa microenvironment is critical for intestinal stem cell self-renewal and reconstruction of the epithelial barrier in inflammatory bowel disease (IBD), where the mechanisms underlying cross-talk between intestinal crypts and the microenvironment remain unclear. Here, we firstly identified mi...

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Detalles Bibliográficos
Autores principales: Song, Lele, Chang, Renxu, Sun, Xia, Lu, Liying, Gao, Han, Lu, Huiying, Lin, Ritian, Xu, Xiaorong, Liu, Zhanju, Zhan, Lixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887198/
https://www.ncbi.nlm.nih.gov/pubmed/33594251
http://dx.doi.org/10.1038/s42003-021-01730-0