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Macrophage-derived EDA-A2 inhibits intestinal stem cells by targeting miR-494/EDA2R/β-catenin signaling in mice
The mucosa microenvironment is critical for intestinal stem cell self-renewal and reconstruction of the epithelial barrier in inflammatory bowel disease (IBD), where the mechanisms underlying cross-talk between intestinal crypts and the microenvironment remain unclear. Here, we firstly identified mi...
Autores principales: | Song, Lele, Chang, Renxu, Sun, Xia, Lu, Liying, Gao, Han, Lu, Huiying, Lin, Ritian, Xu, Xiaorong, Liu, Zhanju, Zhan, Lixing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887198/ https://www.ncbi.nlm.nih.gov/pubmed/33594251 http://dx.doi.org/10.1038/s42003-021-01730-0 |
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