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(89)Zr anti-CD44 immuno-PET monitors  CD44 expression on splenic myeloid cells and HT29 colon cancer cells

CD44 is a cell-surface glycoprotein involved in cell–cell interaction, adhesion, and migration. CD44 is found on colon cancer cells and on immune cells. Previous studies of (89)Zr PET imaging of CD44 have relied on an anti-human antibody (Ab), which can influence biodistribution in murine models. In...

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Detalles Bibliográficos
Autores principales: Park, Jin Won, Jung, Kyung-Ho, Lee, Jin Hee, Moon, Seung Hwan, Cho, Young Seok, Lee, Kyung-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887231/
https://www.ncbi.nlm.nih.gov/pubmed/33594192
http://dx.doi.org/10.1038/s41598-021-83496-3