PLA2R1 promotes DNA damage and inhibits spontaneous tumor formation during aging

Although aging is a major risk factor for most types of cancers, it is barely studied in this context. The transmembrane protein PLA2R1 (phospholipase A2 receptor) promotes cellular senescence, which can inhibit oncogene-induced tumor initiation. Functions and mechanisms of action of PLA2R1 during a...

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Detalles Bibliográficos
Autores principales: Huna, Anda, Griveau, Audrey, Vindrieux, David, Jaber, Sara, Flaman, Jean-Michel, Goehrig, Delphine, Azzi, Lamia, Médard, Jean-Jacques, Djebali, Sophia, Hernandez-Vargas, Hector, Dante, Robert, Payen, Léa, Marvel, Jacqueline, Bertolino, Philippe, Aubert, Sébastien, Dubus, Pierre, Bernard, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887270/
https://www.ncbi.nlm.nih.gov/pubmed/33594040
http://dx.doi.org/10.1038/s41419-021-03468-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887270/
https://www.ncbi.nlm.nih.gov/pubmed/33594040
http://dx.doi.org/10.1038/s41419-021-03468-3

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