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Phosphorylation of SMAD3 in immune cells predicts survival of patients with early stage non-small cell lung cancer
BACKGROUND: The interplay of immune and cancer cells takes place in the tumor microenvironment where multiple signals are exchanged. The transforming growth factor beta (TGFB) pathway is known to be dysregulated in lung cancer and can impede an effective immune response. However, the exact mechanism...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887360/ https://www.ncbi.nlm.nih.gov/pubmed/33589523 http://dx.doi.org/10.1136/jitc-2020-001469 |