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Phosphorylation of SMAD3 in immune cells predicts survival of patients with early stage non-small cell lung cancer

BACKGROUND: The interplay of immune and cancer cells takes place in the tumor microenvironment where multiple signals are exchanged. The transforming growth factor beta (TGFB) pathway is known to be dysregulated in lung cancer and can impede an effective immune response. However, the exact mechanism...

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Detalles Bibliográficos
Autores principales:	Marwitz, Sebastian, Ballesteros-Merino, Carmen, Jensen, Shawn M, Reck, Martin, Kugler, Christian, Perner, Sven, Drömann, Daniel, Goldmann, Torsten, Fox, Bernard A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887360/ https://www.ncbi.nlm.nih.gov/pubmed/33589523 http://dx.doi.org/10.1136/jitc-2020-001469

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