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Two-pore channels affect EGF receptor signaling by receptor trafficking and expression

Two-pore channels (TPCs) are key components for regulating Ca(2+) current from endosomes and lysosomes to the cytosol. This locally restricted Ca(2+) current forms the basis for fusion and fission events between endolysosomal membranes and thereby for intracellular trafficking processes. Here, we st...

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Detalles Bibliográficos
Autores principales: Müller, Thomas, Grossmann, Sonja, Mallmann, Robert Theodor, Rommel, Carolin, Hein, Lutz, Klugbauer, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887427/
https://www.ncbi.nlm.nih.gov/pubmed/33644717
http://dx.doi.org/10.1016/j.isci.2021.102099