Targeting the Opening of Mitochondrial Permeability Transition Pores Potentiates Nanoparticle Drug Delivery and Mitigates Cancer Metastasis

Mitochondria are highly involved in the metastasis of cancer cells. However, low permeability of mitochondria impedes the entry of anti‐cancer drugs. Here, a self‐assembled nanoparticle platform is designed that not only targets the DNA‐intercalating agent doxorubicin to mitochondria but also enhanc...

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Detalles Bibliográficos
Autores principales: Lin, Xi, Li, Lian, Li, Shujie, Li, Qiuyi, Xie, Dandan, Zhou, Minglu, Huang, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887600/
https://www.ncbi.nlm.nih.gov/pubmed/33643797
http://dx.doi.org/10.1002/advs.202002834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887600/
https://www.ncbi.nlm.nih.gov/pubmed/33643797
http://dx.doi.org/10.1002/advs.202002834

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