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Targeting the Opening of Mitochondrial Permeability Transition Pores Potentiates Nanoparticle Drug Delivery and Mitigates Cancer Metastasis
Mitochondria are highly involved in the metastasis of cancer cells. However, low permeability of mitochondria impedes the entry of anti‐cancer drugs. Here, a self‐assembled nanoparticle platform is designed that not only targets the DNA‐intercalating agent doxorubicin to mitochondria but also enhanc...
Autores principales: | Lin, Xi, Li, Lian, Li, Shujie, Li, Qiuyi, Xie, Dandan, Zhou, Minglu, Huang, Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887600/ https://www.ncbi.nlm.nih.gov/pubmed/33643797 http://dx.doi.org/10.1002/advs.202002834 |
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