Endothelial specific deletion of HMGB1 increases blood pressure and retards ischemia recovery through eNOS and ROS pathway in mice()

Recent studies demonstrated HMGB1, an extracellular inflammation molecule, played an important role on endothelial cells. This study aimed to define the role and related mechanism of HMGB1 in endothelial cells. Endothelial-specific deletion of HMGB1(HMGB1ECKO) was generated and Akt/eNOS signaling, r...

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Detalles Bibliográficos
Autores principales: Zhou, Qin, Tu, Tao, Tai, Shi, Tang, Liang, Yang, Hui, Zhu, Zhaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887649/
https://www.ncbi.nlm.nih.gov/pubmed/33582562
http://dx.doi.org/10.1016/j.redox.2021.101890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887649/
https://www.ncbi.nlm.nih.gov/pubmed/33582562
http://dx.doi.org/10.1016/j.redox.2021.101890

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