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A Machine Learning Strategy for Drug Discovery Identifies Anti-Schistosomal Small Molecules

[Image: see text] Schistosomiasis is a chronic and painful disease of poverty caused by the flatworm parasite Schistosoma. Drug discovery for antischistosomal compounds predominantly employs in vitro whole organism (phenotypic) screens against two developmental stages of Schistosoma mansoni, post-in...

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Detalles Bibliográficos
Autores principales: Zorn, Kimberley M., Sun, Shengxi, McConnon, Cecelia L., Ma, Kelley, Chen, Eric K., Foil, Daniel H., Lane, Thomas R., Liu, Lawrence J., El-Sakkary, Nelly, Skinner, Danielle E., Ekins, Sean, Caffrey, Conor R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887754/
https://www.ncbi.nlm.nih.gov/pubmed/33434015
http://dx.doi.org/10.1021/acsinfecdis.0c00754