Structure–Activity Relationships of Pyrazolo[1,5-a]pyrimidin-7(4H)-ones as Antitubercular Agents

[Image: see text] Pyrazolo[1,5-a]pyrimidin-7(4H)-one was identified through high-throughput whole-cell screening as a potential antituberculosis lead. The core of this scaffold has been identified several times previously and has been associated with various modes of action against Mycobacterium tub...

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Detalles Bibliográficos
Autores principales: Oh, Sangmi, Libardo, M. Daben J., Azeeza, Shaik, Pauly, Gary T., Roma, Jose Santinni O., Sajid, Andaleeb, Tateishi, Yoshitaka, Duncombe, Caroline, Goodwin, Michael, Ioerger, Thomas R., Wyatt, Paul G., Ray, Peter C., Gray, David W., Boshoff, Helena I. M., Barry, Clifton E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887755/
https://www.ncbi.nlm.nih.gov/pubmed/33405882
http://dx.doi.org/10.1021/acsinfecdis.0c00851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887755/
https://www.ncbi.nlm.nih.gov/pubmed/33405882
http://dx.doi.org/10.1021/acsinfecdis.0c00851

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