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Combining In Vivo Data with In Silico Predictions for Modeling Hepatic Steatosis by Using Stratified Bagging and Conformal Prediction

[Image: see text] Hepatic steatosis (fatty liver) is a severe liver disease induced by the excessive accumulation of fatty acids in hepatocytes. In this study, we developed reliable in silico models for predicting hepatic steatosis on the basis of an in vivo data set of 1041 compounds measured in ro...

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Detalles Bibliográficos
Autores principales: Jain, Sankalp, Norinder, Ulf, Escher, Sylvia E., Zdrazil, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887803/
https://www.ncbi.nlm.nih.gov/pubmed/33347274
http://dx.doi.org/10.1021/acs.chemrestox.0c00511