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Targeting SNHG3/miR-186-5p reverses the increased m6A level caused by platinum treatment through regulating METTL3 in esophageal cancer

BACKGROUND: Platinum-based chemotherapy is a mainstay for treating esophageal cancer patients. In this manuscript, we have provided clues for influence of platinum on overall m6A level and further investigated the potential regulatory mechanism. METHODS: qRT-PCR was used to measure SNHG3 and miR-186...

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Detalles Bibliográficos
Autores principales: Zhang, Mingxin, Bai, Minghua, Wang, Li, Lu, Ning, Wang, Jia, Yan, Rong, Cui, Manli, Yan, Honglin, Zhang, Lingmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887820/
https://www.ncbi.nlm.nih.gov/pubmed/33596916
http://dx.doi.org/10.1186/s12935-021-01747-9