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Serum transferrin as a biomarker of hepatocyte nuclear factor 4 alpha activity and hepatocyte function in liver diseases

BACKGROUND: Serum transferrin levels represent an independent predictor of mortality in patients with liver failure. Hepatocyte nuclear factor 4 alpha (HNF4α) is a master regulator of hepatocyte functions. The aim of this study was to explore whether serum transferrin reflects HNF4α activity. METHOD...

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Detalles Bibliográficos
Autores principales: Guldiken, Nurdan, Argemi, Josepmaria, Gurbuz, Berivan, Atkinson, Stephen R., Oliverius, Martin, Fila, Petr, Hamesch, Karim, Bruns, Tony, Cabezas, Joaquín, Lozano, Juan J., Mann, Jelena, Cao, Sheng, Mathurin, Philippe, Shah, Vijay H., Trautwein, Christian, Thursz, Mark R., Bataller, Ramon, Strnad, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887823/
https://www.ncbi.nlm.nih.gov/pubmed/33593348
http://dx.doi.org/10.1186/s12916-021-01917-6