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The IL33 receptor ST2 contributes to mechanical hypersensitivity in mice with neuropathic pain

Pathogen infection triggers pain via activation of the innate immune system. Toll-like receptors (TLRs) and Nod-like receptors (NLRs) are the main components of innate immunity and have been implicated in pain signaling. We previously revealed that the TLR2-NLRP3-IL33 pathway mediates inflammatory p...

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Detalles Bibliográficos
Autores principales: Huang, Junting, Gadotti, Vinicius M., Zhang, Zizhen, Zamponi, Gerald W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7888111/
https://www.ncbi.nlm.nih.gov/pubmed/33596932
http://dx.doi.org/10.1186/s13041-021-00752-3