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Fluid shear stress generates a unique signaling response by activating multiple TGFβ family type I receptors in osteocytes

Bone is a dynamic tissue that constantly adapts to changing mechanical demands. The transforming growth factor beta (TGFβ) signaling pathway plays several important roles in maintaining skeletal homeostasis by both coupling the bone‐forming and bone‐resorbing activities of osteoblasts and osteoclast...

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Detalles Bibliográficos
Autores principales: Monteiro, David A., Dole, Neha S., Campos, J. Luke, Kaya, Serra, Schurman, Charles A., Belair, Cassandra D., Alliston, Tamara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7888383/
https://www.ncbi.nlm.nih.gov/pubmed/33570811
http://dx.doi.org/10.1096/fj.202001998R