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Fluid shear stress generates a unique signaling response by activating multiple TGFβ family type I receptors in osteocytes
Bone is a dynamic tissue that constantly adapts to changing mechanical demands. The transforming growth factor beta (TGFβ) signaling pathway plays several important roles in maintaining skeletal homeostasis by both coupling the bone‐forming and bone‐resorbing activities of osteoblasts and osteoclast...
Autores principales: | Monteiro, David A., Dole, Neha S., Campos, J. Luke, Kaya, Serra, Schurman, Charles A., Belair, Cassandra D., Alliston, Tamara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7888383/ https://www.ncbi.nlm.nih.gov/pubmed/33570811 http://dx.doi.org/10.1096/fj.202001998R |
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