FOXP3 and Tip60 Structural Interactions Relevant to IPEX Development Lead to Potential Therapeutics to Increase FOXP3 Dependent Suppressor T Cell Functions

Regulatory T (Treg) cells play a role in the maintenance of immune homeostasis and are critical mediators of immune tolerance. The Forkhead box P3 (FOXP3) protein acts as a regulator for Treg development and function. Mutations in the FOXP3 gene can lead to autoimmune diseases such as Immunodysregul...

Descripción completa

Detalles Bibliográficos
Autores principales: Grover, Payal, Goel, Peeyush N., Piccirillo, Ciriaco A., Greene, Mark I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7888439/
https://www.ncbi.nlm.nih.gov/pubmed/33614551
http://dx.doi.org/10.3389/fped.2021.607292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7888439/
https://www.ncbi.nlm.nih.gov/pubmed/33614551
http://dx.doi.org/10.3389/fped.2021.607292

Ejemplares similares