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Evidence for distinct mechanisms of small molecule inhibitors of filovirus entry

Many small molecules have been identified as entry inhibitors of filoviruses. However, a lack of understanding of the mechanism of action for these molecules limits further their development as anti-filoviral agents. Here we provide evidence that toremifene and other small molecule entry inhibitors...

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Detalles Bibliográficos
Autores principales: Schafer, Adam, Xiong, Rui, Cooper, Laura, Nowar, Raghad, Lee, Hyun, Li, Yangfeng, Ramirez, Benjamin E., Peet, Norton P., Caffrey, Michael, Thatcher, Gregory R. J., Saphire, Erica Ollmann, Cheng, Han, Rong, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7888603/
https://www.ncbi.nlm.nih.gov/pubmed/33539432
http://dx.doi.org/10.1371/journal.ppat.1009312