A humanized CD3ε-knock-in mouse model for pre-clinical testing of anti-human CD3 therapy

Pre-clinical murine models are critical for translating drug candidates from the bench to the bedside. There is interest in better understanding how anti-human CD3 therapy works based on recent longitudinal studies of short-term administration. Although several models have been created in this pursu...

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Detalles Bibliográficos
Autores principales: Crespo, Joel, Koh, Yi Ting, Hu, Ningjie, Moore, Paul A., Bonvini, Ezio, Glasebrook, Andrew L., Martin, Andrea P., Benschop, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7888618/
https://www.ncbi.nlm.nih.gov/pubmed/33596227
http://dx.doi.org/10.1371/journal.pone.0245917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7888618/
https://www.ncbi.nlm.nih.gov/pubmed/33596227
http://dx.doi.org/10.1371/journal.pone.0245917

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